How flashing lights and pink noise might banish Alzheimer’s, improve memory...
Nature News feature 2.28.2018
View ArticlePrime Minister Trudeau visits the MIT Innovation Exhibition in Boston. May...
Prime Minister Trudeau visits the MIT Innovation Exhibition in Boston. May 18, 2018. /// Le premier ministre Trudeau visite l’Exposition sur l’innovation au MIT, à Boston. 18 mai 2018. Credit: Adam Scotti
View ArticleNeuroscientists discover roles of gene linked to Alzheimer’s
People with a gene variant called APOE4 have a higher risk of developing late-onset Alzheimer’s disease: APOE4 is three times more common among Alzheimer’s patients than it is among the general...
View ArticleWith sense of humility, responsibility new MIT postdoc begins HHMI fellowship
Years before he learned that he’d be awarded a highly competitive Hanna H. Gray fellowship from the Howard Hughes Medical Institute, Matheus Victor said he was already feeling fortunate – maybe even a...
View ArticleWith fellowship, postdoc will work to solve Alzheimer’s myelin mystery
Growing up, Joel Blanchard watched his grandfather remain cognitively sharp past the age of 90 but his grandmother develop Alzheimer’s in her 70s. The difference sparked an interest in brain aging that...
View ArticleTsai earns Hans Wigzell Research Foundation Science Prize
The Hans Wigzell Research Foundation announced Jan. 23 that neuroscientist Li-Huei Tsai, Picower Professor and director of The Picower Institute for Learning and Memory at MIT, is the winner of Hans...
View ArticleIn Cell: Brain wave stimulation may improve Alzheimer’s symptoms
By exposing mice to a unique combination of light and sound, MIT neuroscientists have shown that they can improve cognitive and memory impairments similar to those seen in Alzheimer’s patients. This...
View ArticleIn Nature: A comprehensive map of how Alzheimer’s affects the brain
MIT researchers have performed the first comprehensive analysis of the genes that are expressed in individual brain cells of patients with Alzheimer’s disease. The results allowed the team to identify...
View ArticleIn Neuron: Why visual stimulation may work against Alzheimer’s
Several years ago, MIT neuroscientists showed that they could dramatically reduce the amyloid plaques seen in mice with Alzheimer’s disease simply by exposing the animals to light flickering at a...
View ArticleNew Video: An update about our gamma research
In a new video we summarize the recent developments in our GENUS research. We have found that sensory stimulation of 40Hz gamma-frequency rhythms in the brain can help reduce Alzheimer’s disease...
View ArticleStudy pinpoints Alzheimer’s plaque emergence early and deep in the brain
Long before symptoms like memory loss even emerge, the underlying pathology of Alzheimer’s disease, such as an accumulation of amyloid protein plaques, is well underway in the brain. A longtime goal of...
View ArticleTsai elected fellow of National Academy of Inventors
The National Academy of Inventors has selected MIT neuroscientist Li-Huei Tsai, Picower Professor of Neuroscience and director of The Picower Institute for Learning and Memory, as a member of its 2019...
View ArticleScientists eager to explain brain rhythm boost’s broad impact in Alzheimer’s...
The sweeping extent to which increasing 40Hz “gamma” rhythm power in the brain can affect the pathology and symptoms of Alzheimer’s disease in mouse models has been surprising, even to the MIT...
View ArticleStudy finds that aging neurons accumulate DNA damage
MIT neuroscientists have discovered that an enzyme called HDAC1 is critical for repairing age-related DNA damage to genes involved in memory and other cognitive functions. This enzyme is often...
View ArticleStudy finds path for addressing Alzheimer’s blood-brain barrier impairment
By developing a lab-engineered model of the human blood-brain barrier (BBB), neuroscientists at MIT’s Picower Institute for Learning and Memory have discovered how the most common Alzheimer’s disease...
View ArticleOn The Same Wavelength
In a new video, MIT’s School of Science provides an inside look behind the Tsai lab’s discovery that stimulating 40Hz “gamma” frequency brain activity in mice can address Alzheimer’s pathology and...
View ArticleAlzheimer’s risk gene disrupts endocytosis, but another disease-linked gene...
In a new study, a team of scientists based at The Picower Institute for Learning and Memory at MIT and the Whitehead Institute for Biomedical Research reveals evidence showing that the most prominent...
View ArticleNeuroscientists discover a molecular mechanism that allows memories to form
When the brain forms a memory of a new experience, neurons called engram cells encode the details of the memory and are later reactivated whenever we recall it. A new MIT study reveals that this...
View ArticleStudy offers an explanation for why the APOE4 gene enhances Alzheimer’s risk
Gene variant disrupts lipid metabolism, but in experiments the effects were reversed by choline supplements One of the most significant genetic risk factors for developing Alzheimer’s disease is a gene...
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